How to edit a loop sample to create this sound?

I was wondering how certain producers sample a loop and completely add this type of "edit" to it.

An example is this:
The original
http://www.youtube.com/watch?v=LuqEb...?v=LuqEbRzy_t8
Starts at 2:18

The remix with the drop at :41
http://www.youtube.com/watch?v=CVj786Xh7mc"]http://www.youtube.com/watch?v=CVj786Xh7mc

Could someone please explain the effects or what Sikdope did?

Its not a sample at all. Clearly he found the chords from the song and made his own synth that glides.

correctly AllDay
you just need to know the cords
its not hard to do at all
then just choose a synth sound you like to use and play it back