Interesting program called Eye Synth OSC.
OSC control with the Apple ISight camera.
16 step sequencer and Midi Clock Sync.

http://d0cut0uch.com/index.php/eyesynthosc

here is a silly video of it in use.

[ame="http://www.vimeo.com/22035244"]eye synth OSC on Vimeo[/ame]

Divides the screen into 8 quadrants, maybe this would
be great for broad gestures or Modifier states.

l0rdr0ck