I have a setup with s4, maschine and 2 f1s, I had to buy a powered usb hub for the 4 controllers, traktor pro will allow you to use all these controllers for different stuff, you just need to map it all correctly....don't get the s2 in my opinion as I have a friend with one and he always sulks every time he uses mine as it is limted to some of the capabilities not just the it is 2 channel and 4 channel.