I do this and it works out alright for me. Do you sync from your decks or set a master bpm on the clock itself? If you get it about right, and use tempo nudge in Ableton it can work pretty well. I use my DDM as my master MIDI clock for pretty much everything if I'm playing with all my toys at once and so far it's worked fine
As far as dream setups, I'm pretty much there (as per sig) but I'd make a few changes:
* Proper hardware synth (MINIMOOG most likely)
* Pioneer Nexus Mixer
* Decent speakers!
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