If you’ve got a soundcard with lots of I/O (like my audio10) you can already use route audio into/out of Maschine and do what you like to it inside Maschine.
@photojojo: lol, i’m optimistic and think that there will be improvements out of these changes
If it’s on the same computer, what’s the point of sending it all over the USB, the D/A and then the A/D stages and finally back over the USB for additional processing with the Maschine app. It’s just not optimal, but I admit that there are ways to work around these limitations.